LABOAO - Laboratory Equipment and Instruments Manufacturer Supplier in China
+86 18539927482 sales@laboao.com
English
Addressing the biopharmaceutical industry's exceptionally rigorous requirements for sterile environments and process stability, we offer comprehensive process packages spanning the entire workflow—from cell culture (upstream) to protein purification and formulation (downstream). Our solutions strictly adhere to GMP design standards, empowering clients to significantly shorten the transition cycle from R&D to clinical-scale production.
Key Logic
Strain/Cell Expansion → Scaled Fermentation → Separation & Purification → Formulation & Processing
Advantage
Fully recognizing the critical importance of "data traceability," our core equipment supports comprehensive audit trails. Furthermore, we assist clients in completing IQ/OQ/PQ validation protocols, thereby ensuring that production processes remain both compliant and transparent.

Process Flow

  • 01Upstream Culture
    Key EquipmentBioreactors / Fermenters / Incubators
    DescriptionProvides sterile, temperature-controlled, and oxygen-rich environments for bacterial or cell expansion.
  • 02Cell Disruption
    Key EquipmentUltrasonic Cell Disruptors
    DescriptionExtracts target products, such as intracellular proteins and antigens.
  • 03Midstream Harvesting
    Key EquipmentHigh-Speed ​​Tubular Centrifuges / Centrifuges
    DescriptionHarvests microbial biomass or clarifies secreted fluids from culture media.
  • 04Sample Concentration
    Key EquipmentVacuum Concentrators / Nitrogen Concentrators
    DescriptionGently concentrates biological samples while preventing protein denaturation.
  • 05Formulation & Processing
    Key EquipmentFreeze Dryers / Steam Sterilizers (Autoclaves)
    DescriptionPrepares lyophilized powder injectables; ensures the sterility of all materials and equipment in contact with the product.
  • 06Environment/Storage
    Key EquipmentBiosafety Cabinets / Liquid Nitrogen Tanks / Refrigerators
    DescriptionEnsures personnel safety; facilitates the long-term preservation of valuable microbial strains and cell lines.
  • 07Quality Control
    Key EquipmentTotal Organic Carbon (TOC) Analyzers / Ultrapure Water Systems
    DescriptionMonitors the purity of process water; supplies ultrapure water for laboratory applications.

Customers Cases

  • Bioreactor Fermentation Process Optimization System

    ApplicationE. coli fermentation or mammalian cell culture, using a bioreactor to precisely control pH, DO, and temperature to optimize expression.
    Key EquipmentBioreactor Fermenter + Incubator

  • High-Concentration Protein Harvesting System

    ApplicationClarifying and collecting target proteins (bacterial cells or secreted proteins) from fermentation broth, using a high-speed tubular centrifuge to achieve efficient solid-liquid separation.
    Key EquipmentHigh-speed tubular centrifuge + Diaphragm Pump + Filter

  • Vaccine Virus Concentration System

    ApplicationFor live viruses (e.g., influenza, COVID-19 vaccines), using a vacuum concentration centrifuge for gentle, non-denaturing concentration.
    Key EquipmentVacuum concentrator centrifuge + ultrasonic cell disruptor

  • GMP Compliance Formulation Filling Support System

    ApplicationDispensing and pre-treatment of sterile materials in a biosafety cabinet, followed by final steam sterilization.
    Key EquipmentBiosafety cabinet + steam sterilizer + clean bench